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Description
Alexa Fluor® 647 Mouse Anti-Human CD276 Antibody (S-2965)Product Specification Host Mouse Antigen CD276 Synonyms CD276 antigen; 4Ig B7 H3; B7 homolog 3 (B7 H3); Costimulatory molecule; B7H3 Location Membrane Accession Q5ZPR3 Clone Number S 2965 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human monocyte derived mature dendritic cells Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3%
Product Specification
| Host | Mouse |
| Antigen | CD276 |
| Synonyms | CD276 antigen; 4Ig-B7-H3; B7 homolog 3 (B7-H3); Costimulatory molecule; B7H3 |
| Location | Membrane |
| Accession | Q5ZPR3 |
| Clone Number | S-2965 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human monocyte-derived mature dendritic cells |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD276, also known as B7-H3, is a type I transmembrane glycoprotein belonging to the B7 family of immune co-stimulatory molecules that is broadly overexpressed on the cell surface of many solid tumors while showing only limited distribution in normal tissues; it modulates both adaptive and innate immunity by interacting with putative receptors on T cells and NK cells to either inhibit or enhance anti-tumor responses, serves as a marker for cancer progression and poor prognosis, and is actively pursued as a therapeutic target through monoclonal antibodies, antibody–drug conjugates, CAR-T cells, and bispecific T-cell engagers.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
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4.6 ★★★★★
Based on 1956 reviews
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Product Reviews
★★★★★ 5
Absolutely LOVEEE
I loooove this chair. I work from home and it is so comfortable to sit in any position. It is great for sitting criss cross but you can also sit normal or on your knees. Very stable and easy to put together. Great quality
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Reviewed in the United States on April 21, 2026
★★★★★ 5
I LOVE MY Criss Cross Applesauce Office Desk Chair IS THE BEST
Color: Cream, Size: PU Leather(No Wheels)
The Criss Cross Applesauce Office Desk Chair is a unique and innovative addition to any workspace, offering a blend of comfort, functionality, and modern design.
What immediately stands out about this chair is its ergonomic design. The criss-cross frame provides excellent support to the back and promotes proper posture during long hours of sitting. This feature is particularly beneficial for reducing strain on the lower back and promoting overall spinal health, which is essential for those who spend extended periods at their desks.
The chair is upholstered with high-quality materials that offer both durability and comfort. The cushioned seat and backrest provide ample support while maintaining a plush feel, ensuring comfort throughout the workday.
Another notable feature is the adjustable height mechanism, which allows users to customize the chair to their preferred seating position. This versatility ensures that the chair can accommodate individuals of varying heights and preferences, enhancing overall ergonomic comfort.
In terms of aesthetics, the Criss Cross Applesauce chair boasts a modern and sleek design that complements contemporary office decor. Its minimalist appearance blends seamlessly into any workspace environment, adding a touch of style without compromising functionality.
Assembly of the chair is straightforward, with clear instructions provided for easy setup. The sturdy construction and stable base ensure reliability and safety, providing peace of mind for users.
While the chair excels in comfort and design, some users may find the criss-cross frame design to be unconventional compared to traditional office chairs. It's important to consider personal preferences and ergonomic needs when choosing a chair that best suits individual comfort requirements.
Overall, the Criss Cross Applesauce Office Desk Chair combines ergonomic support with modern aesthetics, making it a practical and stylish choice for enhancing comfort and productivity in the workplace. Its blend of functionality, comfort, and contemporary design earns it a recommendation for anyone looking to upgrade their office seating experience.
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Reviewed in the United States on July 10, 2024
★★★★★ 5
Perfect little black chair
I bought this chair for four reasons:
1. My favorite color is black, but the company offers different color options.
2. The height of the chair was exactly what I was looking for. I did not want a tall back for the chair. The chair is close to the ground, which is a plus for me, my back, and my knees as I get older.
3. The chair comes with the option of wheels or no wheels; I chose the no wheels option, as I get dizzy and sick when I spin around for too long.
4. The chair’s wide back and seat design are perfect for me, since I prefer to sit criss-cross in a chair.
Pluses: It reclines, is comfy, and can be cleaned and moved easily.
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Reviewed in the United States on January 7, 2026
★★★★★ 5
Great chair, highly recommend!
Color: Cream, Size: PU Leather(No Wheels), Color: Cream, Size: PU Leather(No Wheels)
Very nice looking chair! It is comfortable, classy, and durable unless you have a cat like mine who used it for his claws. It was easy to put together. All of the hardware was of good quality and everything fit perfectly. My 14 year old daughter even put it together herself. We actually bought two of these. The other one is in my daughter‘s room for her vanity. I highly recommend them whether you’re buying it to sit crisscross or just for roomy comfort. It is a very comfortable chair and looks elegant.
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Reviewed in the United States on March 15, 2026
★★★★★ 5
New Favorite Desk Chair
This chair is exactly what I was looking for! It is simple to put together, very sturdy and very comfortable. I typically tend to sit criss cross while at my desk and I can do that very comfortably with it. Im a bigger girlie so a chair that can hold weight or deal with me shifting positions was very important to me.
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Reviewed in the United States on May 25, 2026
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