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Description
XYMOGEN 5 MTHF 3,400 mcg DFE L-Methylfolate (60 Caps) - Quatrefolic, Cardio, Mood & Methylation SupportExperience high potency L methylfolate with XYMOGEN 5 MTHF. This bioactive folate (Quatrefolic, as 5 MTHF) supports methylation, nervous system health, cardiovascular wellness and mood. Each two capsule serving provides 3,400 mcg DFE of L methylfolate, making it an effective option for individuals who may have limited folic acid conversion or absorption. High potency folate, provided as Quatrefolic l methylfolate (as 5 methyltetrahydrofolate), is the
Experience high-potency L-methylfolate with XYMOGEN 5 MTHF. This bioactive folate (Quatrefolic, as 5-MTHF) supports methylation, nervous system health, cardiovascular wellness and mood. Each two-capsule serving provides 3,400 mcg DFE of L-methylfolate, making it an effective option for individuals who may have limited folic acid conversion or absorption.
- High potency folate, provided as Quatrefolic l-methylfolate (as 5 methyltetrahydrofolate), is the most biologically active form of the water-soluble B vitamin, folic acid.
- Data indicates that supplementing with the L Methyl Folate form increases plasma folate more effectively than folic acid, which may make this product an ideal choice over a standard folic acid supplement.*
- The preferred methyl vitamin b form of folate supplementation due to an array of conditions that can limit conversion or absorption of folic acid. Provided here with 3,400 mcg DFE l-methyl-folate per 2-capsule serving (one capsule is 1,700 or 5 MTHF 1 mg).
- L methylfolate supports nervous system health, oral health, methylation, and cardiovascular health.*
- 5 MTHF capsule formulated to exclude: Wheat, gluten, corn, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from GMOs and artificial preservatives. XYMOGEN methylated folate and vitamin b supplements are practitioner trusted.
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4.9 ★★★★★
Based on 869 reviews
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Product Reviews
★★★★★ 4
My dog loves this toy but…
Color: Grey Bear - Large
This toy has many pros and cons, but it’s my dogs all time favorite toy so I have to give it 4 stars.
Pro:My German Shepard loves this toy, it has no squeaker and she hates squeakers, so she hasn’t tried to destroy it. It’s the perfect size for a large ball. She likes to throw her toys and this one has a pretty decent bounce to it so she can entertain herself.
Cons: the inside is hard rubber, she likes to throw her toys and it hurts when she hits you with it or drops it on your feet. Also a huge hazard to windows and anything breakable.
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Reviewed in the United States on July 12, 2025
★★★★★ 5
Pretty awesome chew toy
Color: Grey Bear - Large
This toy is great!! I have a doodle that shreds everything in sight, including durable toys, but this one stood up to the Teddy test! He easily ripped off the ear/feet bits, but the fabric casing hasn’t come off after a week of play, and I expect the rubber toy inside will be even harder to break.
This is a fairly heavy toy, so it makes a thunk when it drops and is probably not suitable for small dogs. It has a light squeak that is quiet and infrequent enough to not annoy me, and it’s pretty cute too!! it does get soaked in drool pretty fast (and takes forever to dry), but at this point i’m grateful it lasts long enough to get drooled on at all.
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Reviewed in the United States on September 30, 2025
★★★★★ 3
less than 24 hours :/
Color: Grey Bear - Large, Color: Grey Bear - Large
smaller than i expected but had a strong interior that i was pleasantly surprised with. my lil lady very much enjoyed it, however it lasted less than 24 hours before the poor toy was skinned alive :( she loves plushies and she’s obsessed w his skin after tearing him apart. it does have a solid rubber interior that is still good as a toy, however i was hoping its skin would stay on longer than a day :( overall decent toy, 3 stars for being destroyed so quickly. wouldn’t recommend for strong chewers
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Reviewed in the United States on August 7, 2025
★★★★★ 5
Lasts long
Color: Panda Bear - Large
Perfect for super chewer dogs.
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Reviewed in the United States on May 14, 2026
★★★★★ 4
Dachshund said “did I hear indestructible‽ Hold my ball”
Color: Grey Bear - Large
My 15lb Dachshund took this toy as a personal challenge.
He heard me tell his human brother that it’s indestructible on the inside and said “hold my ball” promptly proceeding to schmurder the textile aspect of this adorable toy.
I’d say it took him a total of 23 1/2 minutes to get to the center of this tootsie pop. I’m not even mad tho bc he had no interest in actually ingesting the outer part, and is totally into the inner toy, which is, for him, literally indestructible. It’s solid rubber, has a wild and fun bounce to it on multiple surfaces.
Zodiac rates the squeak 10/10. It’s great especially for when I’m on a call or talking to someone in real life and can’t immediately throw said toy or pay complete attention to him.
In conclusion:
Your dog will probably love it, ((suggest to just keep an eye on them during the schmurder process and make sure you grab all the pieces that come off so none are swallowed))
Depending on your tolerance for squeaker pitch and frequency of squeak, it's a 4/10 in annoyance mostly bc it’s not a long drawn out squeak ((I can not tolerate those toys, they get “lost on top on my fridge” until I get up the courage to throw them out without him seeing)), it’s quick and requires a bit of effort to produce the sound however it’s a very high pitch squeak so it’s all up to your preference. I personally try to buy toys I can tolerate my dog loving on bc when he gets a new toy, it’s his favorite thing for a long time, like, it sleeps on the bed with us for the first month.
Hope your fur child loves this as much as mine did.
Not sure I’ll do the whole two in one toy thing again only he got through it so fast.
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Reviewed in the United States on December 25, 2025