Aminated hollow Prussian blue nanoparticles
SKU: 41089256395

Aminated hollow Prussian blue nanoparticles

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Description

Aminated hollow Prussian blue nanoparticlesProduct Name Name: Aminated hollow Prussian blue nanoparticles Product Overview Prussian Blue (PB for short), also known as Teng's Blue or Ferrocyanide, is a polymeric complex composed of three elements: C, N, and Fe. It generally refers to Ferrocyanide, and its molecular formula is Fe4 [Fe (CN) 6] 3. PB can be used as an antidote for the treatment of thallium and cesium poisoning, and has good biological safety. PB is synthesized by aging

Product Name

Name:Aminated hollow Prussian blue nanoparticles

Product Overview

Prussian Blue (PB for short), also known as Teng's Blue or Ferrocyanide, is a polymeric complex composed of three elements: C, N, and Fe. It generally refers to Ferrocyanide, and its molecular formula is Fe4 [Fe (CN) 6] 3. PB can be used as an antidote for the treatment of thallium and cesium poisoning, and has good biological safety.

PB is synthesized by aging crystallization of potassium ferrocyanide and polyvinylpyrrolidone (PVP). The reaction mainly involves the coordination of CN bonds in potassium ferrocyanide with Fe3+and Fe2+to form crystal nuclei, while PVP is doped with its own CN bonds to form a crystalline structure. Hollow mesoporous Prussian blue (HMPB) is prepared by etching PB with hydrochloric acid, and the cavity structure can be used to load drugs to improve tumor treatment efficiency.

Technical Parameter

Diameter:0-150nm

Solvent:water

Appearance:Blue liquid

Concentration:mg/mL

Product Features

1. Good dispersibility: The raw material PVP, as an amphiphilic substance, is easily soluble in water, resulting in PB with good water dispersibility.

2. Good drug loading capacity: The hollow mesoporous structure obtained by etching of this product has a large surface area and pore volume, which can be used as a nanocarrier to load small molecular substances such as drugs and genes, meeting different biomedical needs.

3. Multiple nano enzyme activities: PB has POD enzyme activity and can decompose H2O2 to produce hydroxyl radicals (· OH); Has SOD enzyme activity and can catalyze the production of H2O2 and O2 from peroxyl groups (· OOH); It has CAT activity and can decompose H2O2 to produce O2.

4. Excellent photothermal conversion efficiency: PB has good light absorption ability at 808 nm, which can convert light energy into heat energy. The generated heat can ablate tumor cells, and the increase in temperature can also enhance nanoenzyme activity.


Application Fields

1. Drug loading: PB, due to its unique hollow mesoporous structure, can load chemotherapy drugs, improve drug loading rate, and achieve targeted drug delivery through surface modification of targeted molecules, thereby improving therapeutic efficacy and slowing down drug side effects on normal cells.

2. Photothermal therapy: PB, due to its special lattice structure, has near-infrared light absorption characteristics and biological safety, and has been widely studied as a new type of photothermal conversion material in the application of tumor ablation.

3. Nanoenzyme therapy: PB has various nanoenzyme activities, such as POD, SOD, CAT enzyme activities, which can clear free radicals, slow down inflammation, alleviate oxidative stress reactions, catalyze hydrogen peroxide to produce oxygen, and alleviate tumor hypoxia.

4. Biomedical imaging: PBNPs have good magnetic resonance imaging (MRI) and photoacoustic imaging (PA) characteristics. At the same time, due to the advantages of their mesoporous structure and surface modification, fluorescence imaging and ultrasound imaging based on PB structure have also been synergistically used for disease diagnosis, leveraging the advantages of multimodal imaging.

Related Information

Please e-mail for the detailed characterization data.

E-mail:[email protected]

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SKU: 41089256395

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Elisa
Omaha, US
★★★★★ 3
Sadly, DNF
Format: Kindle
I read this thru KU. I LOVED the synopsis. And then I began reading... and it was a DNF at 68% after picking it up and putting it down several times because I really loved the main female character. *****SPOILERS***** Pros: The world is unique, intriguing and fun. The primary female character is bad-a** but not a b*tech or a mary sue. The primary female has depth. I really want to know what happens to her even tho it's been weeks and I don't remember her name. The villains to the point I read are pretty good -- an ever present threat of mysterious and possibly many culprits. Cons: Way, way too many points of view. I stopped counting at 7. It's the prime reason why I don't care about most of the characters or remember their names even when I like them. There's just too many points of view so almost none of the characters have enough book space for the author to properly develop them. This literally killed the book for me. Actually it killed my desire to read. For weeks. The main male is more villain than hero. He agreed to marry the main female then locks her up & eschews her for her sister, all while bad mouthing her as unfit to rule when he never spent any time with her getting to know her. He is actually unfit to rule as he is blind to the woes of his own kingdom and starts off a peace mission to secure a ceasefire through marriage by murdering an inn full of people in her country for no real reason. Plus, he constantly makes promises he does not keep. And it's gross of him to pine for the sister behind the main female's back. ***** As much as I really wanted to see what happened to the main female character, it wasn't enough for me to keep trying to slog thru this book. There was a lot of potential here that just fell short. Hence, 3 stars.
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Reviewed in the United States on June 19, 2021
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MaryBeth K
Cuba, US
★★★★★ 5
Fae Courts with High Intrigue
Format: Kindle
This book is one that just builds and builds and then surprises you to no end. You may think you know the villains and then you are jolted in another direction. Princess Reyna is a real gem, strong of character, a fierce fighter, and loyal to her family and kingdom. Just when you think she and Lorcan, well you know, the plot is flipped. Can't wait to see where this goes in book two.
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Reviewed in the United States on July 7, 2023
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Kindle Customer Maureen
Birmingham, US
★★★★★ 4
Slow, sorry but good
Format: Kindle
This was a slow moving book. Lots of character pov chapters, lots of superfluous descriptions and endless courtly appearances stalled this book to start. Once you get into the heart of the story, it takes off. Before you know it the book is done. My favorite character is Reyna. She is so strong. She is true to herself. She gets into a lot of trouble with her headstrong ways but it's entertaining. I have high hopes for Lorcan. He is honorable to a fault. Thane had turned out to be better than I thought but i still don't like him. Eislin is useless. Great plot twists at the end. I'm looking forward too book 2.
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Reviewed in the United States on June 6, 2020
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Faifre6
Dallas, US
★★★★★ 5
Very detailed! Beautiful world building! Strong Heroine!
Format: Kindle
Starts off a little slow and confusing with different POV’s, but starts to all come together towards the middle to make an elaborate plot line and makes it all worth it. Beautiful world building and attention to detail as well as great writing. The cliffhanger was gut wrenching! Can’t wait for the next book!
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Reviewed in the United States on March 4, 2020
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Isabelle
New York, US
★★★★★ 4
Interesting
Format: Kindle
This was a very captivating book once you got into it thoroughly. But the third person perspective was a bit hard to get used to. But as you got into it and followed the different characters, it was interesting and filled with intrigue, conflict and forbidden love. I can’t wait to read the next one and to complete the series.
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Reviewed in the United States on November 12, 2022

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